Zanzhe Yu is an associate chief nephrologist at the Shanghai Jiaotong University School of Medicine and a lecturer at Ottawa-Shanghai joint school of medicine. Her principle research interests are in peritoneal dialysis and the evaluation of fluid status in advanced renal failure.

She is the leading investigator of Renji cohort of Biological Determinants of Peritoneal Dialysis (bio-PD) study. Her research has been supported by the Shanghai Municipal Committee of Science and Technology.

She is in the editor committee of Nature Review Nephrology (Chinese version).